Subgroup for regulatory support of COVID-19 vaccines

Pharmacovigilance actions in the Americas during the COVID-19 pandemic

First phase: October 2020 - March 2021


Objetive:

Provide technical support on the regulatory processes for the adequate introduction and safety surveillance of COVID-19 vaccine and other related medicines.

 

5
National Regulatory Authorities participating

15
Work sessions
 

 

Elaborated resources

 

  • Risk Management Plans and Periodic Safety Reports for COVID-19 Vaccines: Recommendations for Their Request, Preparation, Management, and Assessment

  • COVID-19 Vaccine Pharmacovigilance Dashboard

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  • Consultation Document for Case Definitions: Adverse Events of Special Interest and Adverse Events Following Immunization during COVID-19 Vaccine Introduction

  • Recommendations on Regulatory Processes and Aspects related to the Introduction of Vaccines during the COVID-19 Pandemic and Other Emergencies

 

Second phase: March 2021 to present


Objetive:
 

Support the safety surveillance of COVID-19 vaccines and other related medicines.

 

11
National Regulatory Authorities participating

30
Work sessions
 

 

Elaborated resources

 

  • Consolidated information on AEFI and serious AEFI against COVID-19 applied to the Region of the Americas.

  • Joint evaluation of Risk Management Plans of COVID-19 vaccines.

  • Adaptation of the World Health Organization (WHO) protocol for safety surveillance of molnupiravir and implementation in participating countries.

  • Analysis of the safety information of Covid-19 vaccines used in the Region.

  • Protocol elaboration for the regional vigilance of nirmatrelvir and ritonavir.