Guidelines for the diagnosis, prevention and management of cryptococcal disease in HIV-infected adults, adolescents and children. Policy brief

Cryptococcal meningitis is a serious opportunistic infection which is a major cause of morbidity and mortality in people living with HIV with advanced disease, accounting for an estimated 15% of all AIDS-related deaths globally. An estimated 223,100 cases of cryptococcal meningitis result in 181,000 deaths each year among people living with HIV. Cryptococcal disease is rare in children with HIV, even in areas with a high disease burden among adults.