The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges, Dec 2020

An analysis of the trials for COVID-19 treatment and prevention that are registered from Latin American and the Caribbean (LAC) countries in the International Clinical Trials Registry Platform. It shows a trend towards small repetitive non-rigorous studies that duplicate efforts and drains limited resources without producing meaningful conclusions on the safety and efficacy of the interventions being tested. The study further assesses the challenges to conducting scientifically sound and socially valuable research in the LAC region in order to inform recommendations to encourage clinical trials that are most likely to produce robust evidence during the pandemic.