Epidemiological Update Mpox in the Americas Region - 29 October 2024

Globally, between January 2022 and 30 September 2024, 109,699 confirmed cases of mpox, including 273 deaths, were reported by 123 Member States across the six World Health Organization (WHO) Regions. In September 2024, the number of new cases reported monthly increased by 8% compared to August. Most of the cases reported in September occurred in the African Region (63.6%), and the Americas Region (15.5%).

Between January and 6 October 2024, 7,535 confirmed cases, including 32 deaths, were reported by 16 countries in Africa. The most affected country remains the Democratic Republic of Congo, followed by Burundi and Nigeria. Sixteen countries in the WHO African Region have reported mpox cases in the past six weeks and there are outbreaks considered to be active and ongoing. Clade Ib was first reported in the Democratic Republic of the Congo, and cases have been identified in Burundi, Kenya, Rwanda, and Uganda. This clade was linked to the WHO Director-General's declaration of a public health emergency of international concern (PHEIC) on 14 August 2024. Additionally, this clade has since been identified in confirmed cases outside the WHO African Region, in Germany (n=1 case), India (n=1 case), Sweden (n=1 case), and Thailand (n=1 case).